Correction of Partial Volume Effect in Single Photon Emission Computed Tomography with Hypertrophic Cardiomyopathy

Gated single-photon emission computed tomography detects subendocardial ischemia in hypertrophic cardiomyopathy.

BACKGROUND Patients with hypertrophic cardiomyopathy (HCM) sometimes develop subendocardial ischemia (SEI) in the left ventricle (LV). In the present study it was examined whether volumetric variables obtained by gated single-photon emission computed tomography (SPECT) are useful in detecting exercise-induced SEI in patients with HCM. METHODS AND RESULTS Exercise 99mTc-tetrofosmin myocardial ...

Image Optimization in Single Photon Emission Computed Tomography by Hardware Modifications with Monte Carlo Simulation

Introduction: In Single Photon Emission Computed Tomography (SPECT), the projection data used for image reconstruction are distorted by several factors, including attenuation and scattering of gamma rays, collimator structure, data acquisition method, organ motion, and washout of radiopharmaceuticals. All these make reconstruction of a quantitative SPECT image very difficult. Simulation of a SP...

Single Photon Emission Computed Tomography

Monte Carlo Study of the Effect of Backscatter Materail Thickness on 99mTc Source Response in Single Photon Emission Computed Tomography

Introduction SPECT projections are contaminated by scatter radiation, resulting in reduced image contrast and quantitative errors. Backscatter constitutes a major part of the scatter contamination in lower energy windows. The current study is an evaluation of the effect of backscatter material on FWHM and image quality investigated by Monte Carlo simulation. Materials and Methods SIMIND program...

Attenuation correction in cardiac positron emission tomography and single-photon emission computed tomography.

Quantitation in cardiac positron emission tomography (PET) and single-photon emission computed tomography (SPECT) depends on being able to correct for several physical factors that tend to distort the data. One of the most important of these corrections is the correction for attenuation. For PET, cardiac attenuation correction is a reality, although certain problems remain to be solved. For SPE...